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Zalain 15g (Sertaconazole) Cream


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Generic Name: Sertaconazole
Manufacturer: Ferrer

Sertaconazole is used to treat tinea pedis (athlete’s foot; fungal infection of the skin on the feet and between the toes). Sertaconazole is in a class of medications called imidazoles. It works by slowing the growth of fungi that cause infection.

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Sertaconazole Uses

Sertaconazole topical is an antifungal medication. Sertaconazole topical prevents fungus from growing on the skin.

Sertaconazole topical is used to treat fungal infections of the skin such as athlete’s foot.

Sertaconazole topical may also be used for purposes other than those listed in this medication guide.

Sertaconazole indications

An indication is a term used for the list of condition or symptoms or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache, and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Sertaconazole® (Sertaconazole nitrate) cream, 2%, is indicated for the topical treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by: Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.

How should I use Sertaconazole?

Use Sertaconazole as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Sertaconazole. Talk to your pharmacist if you have questions about this information.
  • Clean and dry the affected area before applying for the medicine.
  • Gently rub the medicine until it is evenly distributed to the affected area and to a small section of healthy skin that surrounds the area.
  • Do not bandage or wrap the affected area unless directed otherwise by your doctor.
  • Wash your hands immediately after using Sertaconazole.
  • To clear up your infection completely, continue using Sertaconazole for the full course of treatment, even if your symptoms get better in a few days. Do not miss any doses.
  • If you miss a dose of Sertaconazole, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Sertaconazole.

Uses of Sertaconazole in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Sertaconazole is used to treat a fungal infection called tenia pedis or athlete’s foot (a fungal infection of the skin on the feet and between the toes) and other fungal and yeast infections.

Sertaconazole description

Sertaconazole nitrate is an antifungal medication of the imidazole class. It is available as a cream to treat skin infections such as athlete’s foot. [Wikipedia]

Sertaconazole dosage

In the treatment of interdigital tinea pedis, Sertaconazole cream, 2%, should be applied twice daily for 4 weeks. Sufficient amount of Sertaconazole cream, 2%, should be applied to cover both the affected areas between the toes and the immediately surrounding healthy skin of patients with interdigital tinea pedis.

Not for ophthalmic, oral, or intravaginal use.

How supplied

Dosage Forms And StrengthsCream, 2%. Each gram of Sertaconazole cream, 2%, contains 17.5 mg of Sertaconazole (as Sertaconazole nitrate, 20 mg) in a white cream base.

Storage And HandlingSertaconazole cream, 2%, is white in color and supplied in tubes in the following size:

60-gram tube NDC 0187-5115-60

Store at 20°C -25°C (68°F -77°F); excursions permitted to 15°-30°C (59°-86°F).

Distributed by: Valeant Pharmaceuticals North America LLC Bridgewater, NJ 08807 Manufactured by: DPT Laboratories, Ltd. San Antonio, TX 78215 Product of Spain. For more information call 1-800-321-4567. Revised: January 2014

Sertaconazole interactions

What other drugs will affect Sertaconazole?

Drug/Laboratory Test Interactions: Potential interactions between SertaconazoleTM Cream, 2%, and other drugs or laboratory tests have not been systematically evaluated.

Sertaconazole side effects

What are the possible side effects of Sertaconazole?

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug, and may not reflect the rates observed in practice.

In clinical trials, cutaneous adverse events occurred in 7 of 297 (2%) subjects (2 of them severe) receiving Sertaconazole® cream, 2%, and in 7 of 291 (2%) subjects (2 of them severe) receiving vehicle. These reported cutaneous adverse events included contact dermatitis, dry skin, burning skin, application site skin tenderness.

In a dermal sensitization trial, 8 of 202 evaluable subjects tested with Sertaconazole® cream, 2%, and 4 of 202 evaluable subjects tested with the vehicle, exhibited a slight erythematous reaction in the challenge phase. There was no evidence of cumulative irritation or contact sensitization in a repeated insult patch test involving 202 healthy volunteers.

Postmarketing Experience

The following adverse reactions have been identified during post-approval use of Sertaconazole cream, 2%. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

In post-marketing surveillance for Sertaconazole cream, 2%, the following was reported:

Cutaneous adverse events: erythema, pruritus, vesiculation, desquamation, and hyperpigmentation.

Sertaconazole contraindications

What is the most important information I should know about Sertaconazole?

SertaconazoleTM Cream, 2%, is contraindicated in patients who have a known or suspected sensitivity to Sertaconazole nitrate or any of its components or to other imidazoles.

Active ingredient matches for Sertaconazole:

Sertaconazole

2 consumers reported useful Was the Sertaconazole drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below-mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, a brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.

Active ingredient matches for Sertaconazole:

Sertaconazole

Unit description / dosage (Manufacturer)Price, USD Ertaczo 2% Cream 30 gm Tube$ 89.28 Ertaczo 2% cream$ 2.60

List of Sertaconazole substitutes (brand and generic names):

Sercos-VT (India) SERCOS-VT vag tab 500 mg x 1’s (Adcock Ingram)$ 1.92 Sertacream (Italy) SERTACREAM 2% CREAM 1 tube / 10 GM cream each (Geymonat)$ 1.27 Sertacream 2% Cream (Geymonat)$ 2.38 Sertaderm (Italy) Sertadie (Italy) Sertagyn (Italy) Sertakon (India) Sertakon 2% CRM / 10g (Wockhardt (Derma)) Sertakon 5% CRM / 10g (Wockhardt (Derma)) SERTAKON 2% CREAM 1 tube / 10 GM cream each (Wockhardt (Derma))$ 2.39 SERTAKON cream 2 % x 10g (Wockhardt (Derma))$ 1.98 SERTAKON cream 5 % x 10g (Wockhardt (Derma)) SERTALIN SERTALIN CREAM 1 tube / 10 GM cream each (Lincoln Pharmaceuticals Ltd)$ 1.30 Sertalin NA Cream (Lincoln Pharmaceuticals Ltd)$ 3.33 Sertazol (Georgia) Sertazol 10 mg Cream (Ranbaxy Laboratories Ltd.,)$ 1.27 SERTAZOL 2% CREAM 1 tube / 10 GM cream each (Ranbaxy Laboratories Ltd.,)$ 1.39 SERTAZOL V SERTAZOL V 500 MG TABLET 1 strip / 10 tablets each (Ranbaxy Laboratories Ltd)$ 1.75 Sertopic (Portugal) SETRABET SETRABET 2% W/W CREAM 1 tube / 15 GM cream each (Med Manor Organics Pvt Ltd)$ 2.06 SETRABET 2% W/W CREAM 1 tube / 30 GM cream each (Med Manor Organics Pvt Ltd)$ 3.97 Setrabet 2% w/w Cream (Med Manor Organics Pvt Ltd)$ 2.06 Tromderm (Chile) Cream; Topical; Sertaconazole Nitrate 2% (Silesia) Velconazole 2% (Egypt) Zalain (Argentina, Bulgaria, Chile, China, Costa Rica, Dominican Republic, El Salvador, Georgia, Guatemala, Honduras, Hong Kong, Nicaragua, Panama, Peru, Philippines, Russian Federation, Singapore, Slovakia, Spain, Taiwan, Thailand, Turkey, Venezuela) Cream; Topical; Sertaconazole Nitrate 2% (Ferrer) Suppositories; Vaginal; Sertaconazole Nitrate 300 mg (Ferrer) Zalain 2%/20g – 1 Cream (Ferrer)$ 20.00 Zalain 300mg – 1 Vaginal ovules (Ferrer)$ 25.00 Zalain 300 mg x 1’s (Ferrer) Zalain 500 mg x 20’s (Ferrer) Zalain 2 % x 5 g (Ferrer)$ 3.10 Zalain 2 % x 10 g (Ferrer)$ 5.67 Zalain 2 % x 20 g (Ferrer) Zalain / w/ applicator 500 mg x 1’s (Ferrer) ZALAIN 300MG PESSARIES 1 packet / 1 pessaries each (Ferrer)$ 1.83 Zalain vag ovule 300 mg 1’s (Ferrer) Zalain vag tab 500 mg / w/ applicator 1’s (Ferrer) Zalain 300mg Pessaries (Ferrer)$ 1.83 Zalaïn (Germany) Cream; Topical; Sertaconazole Nitrate 2% Suppositories; Vaginal; Sertaconazole Nitrate 300 mg Zalain 2%/20g – 1 Cream$ 20.00 Zalain 300mg – 1 Vaginal ovules$ 25.00 Zalain 300 mg x 1’s Zalain 500 mg x 20’s See 118 substitutes for Sertaconazole

References

  1. PubChem. “Sertaconazole”. https://pubchem.ncbi.nlm.nih.gov/com…
  2. DrugBank. “Sertaconazole”. http://www.drugbank.ca/drugs/DB01153
  3. MeSH. “Antifungal Agents”. https://www.ncbi.nlm.nih.gov/mesh/68…

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