Tydol (Tapentadol) 100mg

Product Name: Tydol
Price/Tab: $ 0.60
Active Ingredient: Tapentatol
Manufacturer: Hab Pharma
Drug Type: opiate (narcotic) analgesics
Common brand names: Tydlol, Nucynta, Palexia, Yantil, Tapenta, Tapal, Aspadol,

Tapentadol is used to help relieve moderate to severe short-term pain (such as pain from an injury or after surgery). It belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain.




Tapentadol For Pain Relief

TYDOL 100 mg tablet is used to treat moderate to severe pain.

What is Tapentadol?

Tapentadol (Tapentadol) is an opioid pain medication. An opioid is sometimes called a narcotic.

Tapentadol is used to treat moderate to severe pain.

The extended-release form of Tapentadol is for around-the-clock treatment of pain that is not controlled by other medicines. It is not for use on an as-needed basis for pain.

Tapentadol may also be used for purposes not listed in this medication guide.

Common brand names: Tydlol, Nucynta, Palexia, Yantil, Tapenta, Tapal, Aspadol, 

Tapentadol indications

An indication is a term used for the list of conditions or symptoms or illnesses for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache, and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Tapentadol® ER (Tapentadol) is indicated for the management of:

  • ​pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate
  • ​neuropathic pain associated with diabetic peripheral neuropathy (DPN) in adults severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Tapentadol ​Limitations of Usage

  • ​Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with extended-release opioid formulations, reserve Tapentadol® ER for use in patients for whom alternative treatment options (e.g., non-opioid analgesics or immediate-release opioids) are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain.
  • ​Tapentadol® ER is not indicated as an as-needed (prn) analgesic.

Tapentadol Palexia

Tapentadol for Palexia

Tapentadol – the active substance in PALEXIA – is a strong painkiller which belongs to the class of opioids. PALEXIA is used in adults for the treatment of moderate to severe pain of recent onset that can only be adequately managed with an opioid painkiller.

How should I use Tapentadol?

Use Tapentadol extended-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Tapentadol extended-release tablets come with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Tapentadol extended-release tablets refilled.
  • Take Tapentadol extended-release tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Tapentadol extended-release tablets must only be taken by mouth. Do not inject or snort Tapentadol extended-release tablets.
  • Do not swallow more than 1 tablet at a time. If your dose requires more than 1 tablet, take only 1 tablet at a time.
  • Swallow Tapentadol extended-release tablets whole. Do not break, cut, crush, chew, or dissolve the tablet before swallowing it. Contact your doctor if you cannot swallow Tapentadol extended-release tablets whole.
  • Do not presoak, lick, or wet the tablet before you place it in your mouth. Take each tablet with enough water to be sure that it can be completely swallowed immediately after you place it in your mouth.
  • Do not suddenly stop taking Tapentadol extended-release tablets. You may have an increased risk of withdrawal symptoms (eg, nausea, vomiting, diarrhea, anxiety, shivering). If you need to stop Tapentadol extended-release tablets, your doctor will gradually lower your dose.
  • Tapentadol extended-release tablets works best if it is taken at the same time(s) each day. Do not miss any doses.
  • If you miss a dose of Tapentadol extended-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Do not take more than your prescribed dose in 24 hours.

Ask your health care provider any questions you may have about how to use Tapentadol extended-release tablets.

Uses of Tapentadol in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after a few days, some drugs need to be continued for a prolonged period to get the benefit from it.

Use: Labeled Indications

Neuropathic pain associated with diabetic peripheral neuropathy: Extended-release: Management of neuropathic pain associated with diabetic peripheral neuropathy (DPN) severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Note: Tapentadol ER is generally not recommended as first or second-line therapy due to a high risk for addiction and safety concerns compared to modest pain reduction (Pop-Busui 2017).

Tapentadol Pain management:

Immediate release: Management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate in adults.

Extended-release: Management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatments are inadequate.

Limitations of use: Reserve Tapentadol for use in patients for whom alternative treatment options (eg, nonopioid analgesics, opioid combination products) are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain. Tapentadol ER is not indicated as an as-needed analgesic.

Tapentadol description

Opioid analgesic for the treatment of moderate to severe pain. FDA approved on Nov 20, 2008.

Tapentadol dosage

  • TYDOL 100MG TABLET Swallow the tablets with a glass of water. You may take the tablets either on an empty stomach or with food.
  • TYDOL 100MG TABLET works by changing the way the brain and nervous system respond to pain.

Tapentadol® oral solution is available in one concentration: 20 mg/mL.

Take care when prescribing and administering Tapentadol® oral solution to avoid dosing errors, which could result in accidental overdose and death. Take care to ensure the proper dose is communicated and dispensed. Include the dose in milliliters (mL) and milligrams (mg) when writing prescriptions. Always use the enclosed calibrated oral syringe when administering Tapentadol® oral solution to ensure the dose is measured and administered accurately.

Individualization Of Dosage

As with any opioid drug product, adjust the dosing regimen for each patient individually, taking into account the patient’s prior analgesic treatment experience. In the selection of the initial dose of Tapentadol, give attention to the following:

  • the total daily dose, potency and specific characteristics of the opioid the patient has been taking previously;
  • the reliability of the relative potency estimate used to calculate the equivalent morphine sulfate dose needed;
  • the patient’s degree of opioid tolerance;
  • the general condition and medical status of the patient;
  • concurrent medications;
  • the type and severity of the patient’s pain;
  • risk factors for abuse, addiction or diversion, including a prior history of abuse, addiction or diversion.

The following dosing recommendations, therefore, can only be considered suggested approaches to what is actually a series of clinical decisions over time in the management of the pain of each individual patient. Continual re-evaluation of the patient receiving Tapentadol is important, with special attention to the maintenance of pain control and the relative incidence of side effects associated with therapy. During chronic therapy, especially for non-cancer-related pain, periodically re-assess the continued need for the use of opioid analgesics.

During periods of changing analgesic requirements, including initial titration, frequent contact is recommended between physician, other members of the healthcare team, the patient, and the caregiver/family. Monitor the patient for signs of respiratory or central nervous system depression.

Initiation Of Therapy

The dose is 2.5 mL (equivalent to 50 mg), 3.75 mL (equivalent to 75 mg), or 5 mL (equivalent to 100 mg) every 4 to 6 hours depending upon pain intensity.

On the first day of dosing, the second dose may be administered as soon as one hour after the first dose, if adequate pain relief is not attained with the first dose. Subsequent dosing is 2.5 mL (equivalent to 50 mg), 3.75 mL (equivalent to 75 mg), or 5 mL (equivalent to 100 mg) every 4 to 6 hours and should be adjusted to maintain adequate analgesia with acceptable tolerability.

Daily doses greater than 700 mg on the first day of therapy and 600 mg on subsequent days have not been studied and are not recommended.

Tapentadol® may be given with or without food.

Renal Impairment

Use of Tapentadol® in patients with severe renal impairment is not recommended.

No dosage adjustment is recommended in patients with mild or moderate renal impairment.

Hepatic Impairment

The safety and efficacy of Tapentadol® has not been studied in patients with severe hepatic impairment (Child-Pugh Score 10-15) and use in this population is not recommended.

Initiate treatment of patients with moderate hepatic impairment (Child-Pugh Score 7 to 9) with 50 mg no more frequently than once every 8 hours (maximum of three doses in 24 hours). Further treatment should reflect maintenance of analgesia with acceptable tolerability, to be achieved by either shortening or lengthening the dosing interval.

No dosage adjustment is recommended in patients with mild hepatic impairment (Child-Pugh Score 5 to 6).

Elderly Patients

In general, recommended dosing for elderly patients with normal renal and hepatic function is the same as for younger adult patients with normal renal and hepatic function. Because elderly patients are more likely to have decreased renal and hepatic function, consideration should be given to starting elderly patients with the lower range of recommended doses.

Cessation Of Therapy

When the patient no longer requires therapy with Tapentadol, gradually taper the dose to prevent signs and symptoms of withdrawal in the physically dependent patient.

How to take tapentadol?

  • Before starting the treatment of chronic, read the manufacturer’s printed information sheet inside the package. It will give you more information about tapentadol and will provide you with a complete list of side effects you may encounter from taking it.
  • Take Tapentadol exactly as your doctor tells you. Instructions for taking it will be printed on the packaging label to remind you of what the doctor told you. The usual short-term pain relief dose is 50 mg every 4-6 hours if necessary. You will be provided with standard tablets or oral liquid medicine. If you are taking Tapentadol for a long-term painful condition, you will be prescribed a tablet brand called Palexia® SR (“SR” refers to the slow release as it was specially formulated to release the medicine slowly to give you more painkiller effect). You will need to take these tablets twice a day.
  • There are many different strengths of tablets available, so every time you collect a new resource, it’s a good idea to check out the poster to make sure it’s the power you expect. If you are not sure, ask your pharmacist for advice.
  • Swallow the tablet with a drink of water. You can take tapentadol (Nucynta) before or after food. Swallow the tablet whole – do not crush or chew Tabentadol tablets.
  • If you forget to take a dose of this medicine, you should take it as soon as you remember. If you remember, it’s almost time for the next dose, then take the next dose when it’s due but leave the missed dose. Do not take two doses together to make up for the missed dose.

If you want to buy this medicine, you can Order Tapentadol Online online directly here at our store.

Concentration and Dispensing: The oral solution contains 20 mg Tapentadol per milliliter (mL) and prescriptions should be written in milliliters (mL) and milligrams (mg). An oral syringe is supplied with dose marks corresponding directly to 2.5 mL (equals 50 mg) oral solution, 3.75 mL (equals 75 mg) oral solution, and 5 mL (equals 100 mg) oral solution.

Inform patients of the availability of FDA-approved patient labeling, Instructions for Use, for step-by-step instructions for patients on how to use the medicine bottle and the oral syringe.

How supplied

Dosage Forms And Strengths

Tapentadol® oral solution: 20 mg/mL oral solution in 100 mL and 200 mL fill bottles with child-resistant closure.

Tapentadol® oral solution, 20 mg/mL, is available as a clear, colorless solution. Supplied with calibrated syringe:

Bottles of 100 mL (NDC 50458-817-01)

Bottles of 200 mL (NDC 50458-817-02)

Storage And Handling

Store up to 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Store the oral solution bottle upright after opening.

Keep Tapentadol® in a secure place out of reach of children.

Tapentadol® oral solution that is no longer needed should be destroyed by flushing down the toilet.

Manufactured by: Patheon Pharmaceuticals, Inc. Cincinnati, OH 45237 Manufactured for: Janssen Pharmaceuticals, Inc. Titusville, NJ 08560. Revised: November 2014

Tapentadol interactions

Tapentadol® is mainly metabolized by glucuronidation. The following substances have been included in a set of interaction studies without any clinically significant finding: acetaminophen, acetylsalicylic acid, naproxen and probenecid.

The pharmacokinetics of Tapentadol were not affected when gastric pH or gastrointestinal motility were increased by omeprazole and metoclopramide, respectively.

Tapentadol Precautions

Pregnancy: Do not take this medicine if you are pregnant or plan to become pregnant.
Alcohol: Do not drink alcohol.
Driving: Do not drive, use tools or machinery if you feel drowsy, dizzy, have blurred vision or a slow reaction time.
Kidney: Use with caution in patients with mild to moderate renal impairment. Not recommended for use in severe renal impairment.
LIver: Use with caution in patients with moderate hepatic impairment (dosage adjustment required). Not recommended for use in severe hepatic impairment.


To make sure this medicine is safe for you, tell your doctor if you have ever had:

  • any type of breathing problem or lung disease
  • a head injury, brain tumor, or seizures
  • drug addiction, or mental illness
  • urination problems
  • problems with your gallbladder, pancreas, or thyroid

Alcohol, Other Opioids, And Drugs of Abuse

Due to its mu-opioid agonist activity, Tapentadol® may be expected to have additive effects when used in conjunction with alcohol, other opioids, or illicit drugs that cause central nervous system depression, respiratory depression, hypotension, and profound sedation, coma or death. Instruct patients not to consume alcoholic beverages or use prescription or non-prescription products containing alcohol, other opioids, or drugs of abuse while on Tapentadol® therapy.

Monoamine Oxidase Inhibitors

Tapentadol® is contraindicated in patients who are receiving monoamine oxidase (MAO) inhibitors or who have taken them within the last 14 days due to potential additive effects on norepinephrine levels which may result in adverse cardiovascular events.

CNS Depressants

Concurrent use of Tapentadol® and other central nervous system (CNS) depressants including sedatives or hypnotics, general anesthetics, phenothiazines, tranquilizers, and alcohol can increase the risk of respiratory depression, hypotension, profound sedation or coma. Monitor patients receiving CNS depressants and Tapentadol® for signs of respiratory depression and hypotension. When such combined therapy is contemplated, start Tapentadol® at 1/3 to ½ of the usual dosage and consider using a lower dose of the concomitant CNS depressant.

Serotonergic Drugs

There have been post-marketing reports of serotonin syndrome with the concomitant use of Tapentadol and serotonergic drugs (e.g., SSRIs and SNRIs). Caution is advised when Tapentadol® is co-administered with other drugs that may affect serotonergic neurotransmitter systems such as SSRIs, SNRIs, MAOIs, and triptans. If concomitant treatment of Tapentadol® with a drug affecting the serotonergic neurotransmitter system is clinically warranted, careful observation of the patient is advised.

Mixed Agonist/Antagonist Opioid Analgesics

The concomitant use of Tapentadol® with mixed agonist/antagonists (e.g., butorphanol, nalbuphine, and pentazocine) and partial agonists (e.g., buprenorphine) may precipitate withdrawal symptoms. Avoid the use of agonist/antagonists and partial agonists with Tapentadol®.


The use of Tapentadol® with anticholinergic products may increase the risk of urinary retention and/or severe constipation, which may lead to paralytic ileus.

Drug Abuse And Dependence Controlled Substance

Tapentadol® contains Tapentadol, a Schedule II controlled substance with a high potential for abuse similar to fentanyl, methadone, morphine, oxycodone, and oxymorphone. Tapentadol® is subject to misuse, abuse, addiction, and criminal diversion.


All patients treated with opioids require careful monitoring for signs of abuse and addiction because the use of opioid analgesic products carries the risk of addiction even under appropriate medical use.

Drug abuse is the intentional non-therapeutic use of an over-the-counter or prescription drug, even once, for its rewarding psychological or physiological effects. Drug abuse includes, but is not limited to the following examples: the use of a prescription or over-the-counter drug to get “high”, or the use of steroids for performance enhancement and muscle build-up.

Drug addiction is a cluster of behavioral, cognitive, and physiological phenomena that develop after repeated substance use and include: a strong desire to take the drug, difficulties in controlling its use, persisting in its use despite harmful consequences, a higher priority given to drug use than to other activities and obligations, increased tolerance, and sometimes a physical withdrawal.

“Drug seeking” behavior is very common in addicts, and drug abusers. Drug-seeking tactics include emergency calls or visits near the end of office hours, refusal to undergo appropriate examination, testing or referral, repeated claims of loss of prescriptions, tampering with prescriptions and reluctance to provide prior medical records or contact information for other treating physician(s). “Healthcare professional shopping” (visiting multiple prescribers) to obtain additional prescriptions is common among drug abusers, people suffering from untreated addiction and criminals seeking drugs to sell.

Abuse and addiction are separate and distinct from physical dependence and tolerance. Physicians should be aware that addiction may not be accompanied by concurrent tolerance and symptoms of physical dependence in all addicts. In addition, abuse of opioids can occur in the absence of true addiction and is characterized by misuse for non-medical purposes, often in combination with other psychoactive substances.

Tapentadol® can be diverted for non-medical use into illicit channels of distribution. Careful record-keeping of prescribing information, including quantity, frequency, and renewal requests, as required by law, is strongly advised.

Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs.


Both tolerance and physical dependence can develop during chronic opioid therapy. Tolerance is the need for increasing doses of opioids to maintain a defined effect such as analgesia (in the absence of disease progression or other external factors). Tolerance may occur to both the desired and undesired effects of drugs, and may develop at different rates for different effects.

Physical dependence results in withdrawal symptoms after abrupt discontinuation or a significant dose reduction of a drug. Withdrawal also may be precipitated through the administration of drugs with opioid antagonist activity, e.g., naloxone, nalmefene, or mixed agonist/antagonist analgesics (pentazocine, butorphanol, buprenorphine, nalbuphine). Physical dependence may not occur to a clinically significant degree until after several days to weeks of continued opioid usage. Some or all of the following can characterize this syndrome: restlessness, lacrimation, rhinorrhea, yawning, perspiration, chills, piloerection, myalgia, mydriasis, irritability, anxiety, backache, joint pain, weakness, abdominal cramps, insomnia, nausea, anorexia, vomiting, diarrhea, increased blood pressure, respiratory rate, or heart rate. Withdrawal symptoms may be reduced by tapering Tapentadol®.

Infants born to mothers physically dependent on opioids will also be physically dependent and may exhibit respiratory difficulties and withdrawal symptoms.

Tapentadol side effects

  • headache
  • heartburn
  • stomach pain
  • dry mouth
  • excessive tiredness
  • anxiety
  • drowsiness
  • difficulty falling asleep or staying asleep
  • abnormal dreams
  • irritability
  • sudden feeling of warmth

Clinical Studies Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. Based on data from nine Phase 2/3 studies that administered multiple doses (seven placebo- and/or active-controlled, one noncontrolled and one Phase 3 active-controlled safety study) the most common adverse reactions (reported by ≥ 10% in any Tapentadol® dose group) were: nausea, dizziness, vomiting and somnolence.

The most common reasons for discontinuation due to adverse reactions in the studies described above (reported by ≥ 1% in any Tapentadol® dose group) were dizziness (2.6% vs. 0.5%), nausea (2.3% vs. 0.6%), vomiting (1.4% vs. 0.2%), somnolence (1.3% vs. 0.2%) and headache (0.9% vs. 0.2%) for Tapentadol®- and placebo-treated patients, respectively.

Seventy-six percent of Tapentadol®-treated patients from the nine studies experienced adverse events.

Tapentadol® was studied in multiple-dose, active- or placebo-controlled studies, or noncontrolled studies (n = 2178), in single-dose studies (n = 870), in open-label study extension (n = 483) and in Phase 1 studies (n = 597). Of these, 2034 patients were treated with doses of 50 mg to 100 mg of Tapentadol® dosed every 4 to 6 hours.

The data described below reflect exposure to Tapentadol® in 3161 patients, including 449 exposed for 45 days. Tapentadol® was studied primarily in placebo- and active-controlled studies (n = 2266, and n = 2944, respectively). The population was 18 to 85 years old (mean age 46 years), 68% were female, 75% white and 67% were postoperative. Most patients received Tapentadol® doses of 50 mg, 75 mg, or 100 mg every 4 to 6 hours.

Table 1 Adverse Reactions Reported by ≥ 1% of Tapentadol®-Treated Patients In Seven Phase 2/3 Placebo- and/or Oxycodone-Controlled, One Non-controlled, and One Phase 3 Oxycodone-Controlled Safety, Multiple-Dose Clinical Studies

Post-marketing Experience

The following additional adverse reactions have been identified during post-approval use of Tapentadol®. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably.

Gastrointestinal disorders: diarrhea

Psychiatric disorders: hallucination, suicidal ideation, panic attack

Cardiac disorders: palpitations

Anaphylaxis, angioedema, and anaphylactic shock have been reported very rarely with ingredients contained in Tapentadol®. Advise patients how to recognize such reactions and when to seek medical attention.

Tapentadol contraindications

What is the most important information I should know about Tapentadol?

You should not use this medication if you are allergic to Tapentadol, or if you have severe liver or kidney disease, if you are having an asthma attack, or if you have a bowel obstruction called paralytic ileus.

Do not use Tapentadol if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Tapentadol may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

Do not drink alcohol while you are taking Tapentadol. Dangerous side effects or death can occur when alcohol is combined with narcotic pain medicine. Check your food and medicine labels to be sure these products do not contain alcohol.

Never take Tapentadol in larger amounts, or for longer than recommended by your doctor. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how Tapentadol will affect you.

Do not stop using Tapentadol suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Tapentadol.

Active ingredient matches for Tapentadol:


Unit description / dosage (Manufacturer)Price, USD Tablet; Oral; Tapentadol Hydrochloride 50 mg Tablet; Oral; Tapentadol Hydrochloride 75 mg Tablet; Oral; Tapentadol Hydrochloride 100 mg

Nucynta, Tapentadol Important information

You should not use Nucynta if you have severe breathing problems, or a bowel obstruction called paralytic ileus.

Do not use Nucynta if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Tapentadol can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take this medicine in larger amounts, or for longer than prescribed. Do not crush, break, or open an extended-release tablet. Swallow it whole to avoid exposure to a potentially fatal dose.

Tapentadol may be habit-forming, even at regular doses.

Take this medicine exactly as prescribed by your doctor. Never share the medicine with another person. MISUSE OF NARCOTIC PAIN MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

Tell your doctor if you are pregnant

Nucynta may cause life-threatening withdrawal symptoms in a newborn if the mother has taken this medicine during pregnancy.

Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

List of Tapentadol substitutes (brand and generic names):

Tapenta (Japan) Tapenta 50mg Tablet (Zuventus)$ 0.17 Tapentadol Extended-Release Tablets TAPOSER (India) TAPOSER tab 50 mg x 10’s (Intra Labs)$ 1.90 TAPOSER tab 75 mg x 10’s (Intra Labs) TAPOSER tab 100 mg x 10’s (Intra Labs) TOP MONO TOP MONO 25MG TABLET 1 strip / 10 tablets each (Micro Labs Ltd)$ 0.79 TOP MONO 50MG TABLET 1 strip / 10 tablets each (Micro Labs Ltd)$ 1.57 Top Mono 50mg Tablet (Micro Labs Ltd)$ 0.16 Transdol (India) Transdol 50 mg Tablet (Lupin Laboratories Ltd.)$ 0.16 Transdol 100 mg Tablet (Lupin Laboratories Ltd.)$ 0.32 Transdol 50mg FC-TAB / 10 (Lupin Laboratories Ltd.)$ 1.57 TRANSDOL 50MG TABLET 1 strip / 10 tablets each (Lupin Laboratories Ltd.)$ 1.58 TRANSDOL film-coated tab 50 mg x 10’s (Lupin Laboratories Ltd.)$ 1.57 Transdol 50mg Tablet (Lupin Laboratories Ltd.)$ 0.16 TRIMPEN (India) TRIMPEN tab 50 mg x 10’s (Orion) Tyndr-50 Plus (India) Tyndr-50 Plus Tapentadol 5 mg, paracetamol325 mg. TAB / 10 (Aamorb (Sioux))$ 2.06 TYNDR-50 PLUS tab 10’s (Aamorb (Sioux))$ 2.06 VORTH TP VORTH TP 100 MG TABLET 1 strip / 10 tablets each (Glenmark Pharmaceuticals Ltd)$ 1.64 VORTH TP 50 MG TABLET 1 strip / 10 tablets each (Glenmark Pharmaceuticals Ltd)$ 2.06 VORTH TP 50 MG TABLET ER 1 strip / 10 tablet ers each (Glenmark Pharmaceuticals Ltd)$ 2.09 VORTH TP 75 MG TABLET 1 strip / 10 tablets each (Glenmark Pharmaceuticals Ltd)$ 1.41 Vorth TP 100mg Tablet (Glenmark Pharmaceuticals Ltd)$ 0.16 Vorth TP 50mg Tablet (Glenmark Pharmaceuticals Ltd)$ 0.23 Vorth TP 50mg Tablet ER (Glenmark Pharmaceuticals Ltd)$ 0.21 Vorth TP 75mg Tablet (Glenmark Pharmaceuticals Ltd)$ 0.14 Vorth-TP (India) Vorth-TP 50mg FC-TAB / 10 (Glenmark (Integrace))$ 1.57 Vorth-TP 75mg FC-TAB / 10 (Glenmark (Integrace))$ 2.38 Vorth-TP 100mng FC-TAB / 10 (Glenmark (Integrace))$ 3.16 VORTH-TP film-coated tab 50 mg x 10’s (Glenmark (Integrace))$ 1.57 VORTH-TP film-coated tab 75 mg x 10’s (Glenmark (Integrace))$ 2.38 VORTH-TP film-coated tab 100 mg x 10’s (Glenmark (Integrace))$ 3.16 Vorth-TP Plus (India) Vorth-TP Plus Tapentadol 50 mg, paracetamol325 mg. FC-TAB / 10 (Glenmark)$ 1.73 VORTH-TP PLUS film-coated tab 10’s (Glenmark)$ 1.73 Yantil (Belgium, Netherlands) Yantil retard (Germany) Zyntap (India) Zyntap 50 mg Tablet (Cadila Pharmaceuticals Ltd.)$ 0.16 Zyntap 50mg FC-TAB / 10 (Cadila Pharmaceuticals Ltd.)$ 1.57 Zyntap 75mg FC-TAB / 10 (Cadila Pharmaceuticals Ltd.)$ 2.21 Zyntap 100mg FC-TAB / 10 (Cadila Pharmaceuticals Ltd.)$ 3.16 ZYNTAP film-coated tab 50 mg x 10’s (Cadila Pharmaceuticals Ltd.)$ 1.57 ZYNTAP film-coated tab 75 mg x 10’s (Cadila Pharmaceuticals Ltd.)$ 2.21 ZYNTAP film-coated tab 100 mg x 10’s (Cadila Pharmaceuticals Ltd.)$ 3.16 See 182 substitutes for Tapentadol


  1. PubChem. “Tapentadol”. https://pubchem.ncbi.nlm.nih.gov/com…
  2. DrugBank. “Tapentadol”. http://www.drugbank.ca/drugs/DB06204
  3. MeSH. “MeSH Tree: MeSH (Medical Subject Headings) PubMed.”. http://www.nlm.nih.gov/mesh/meshhome…

Read more about Tapentadol here

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