Arimidex, Anastrazole Description
- Product and Laboratory: Anastrozole (Arimidex) by A-Tech Labs
- Effects: Anti-estrogen, decreases fat build-up, decreases water retention
- Ingredients: Anastrozole
- Form: Oral
- Concentration: 1 mg/tab
- Presentation: 100 tabs
- Dosage: 0.5-1mg every other day
Beginners Intermediate Advanced Female 0.5mg EOD 1mg EOD 1mg EOD N/A
- Protection during treatment: N/A
- Pct post cycle therapy: N/A
- Stack: Letrozole/HCG/Testosterone
- Level: Suitable for all users
Anastrozole, the active ingredient in Arimidex, is an adjunct therapy in the treatment of hormone receptor-positive early breast cancer in postmenopausal women and as a first-line treatment for hormone receptor-positive (or hormone receptor-unknown) locally advanced or metastatic breast cancer in postmenopausal women.10 It may also be used in the treatment of advanced breast cancer in postmenopausal women who experience disease progression despite treatment with tamoxifen.11,10
How Anastrozole works
Anastrozole prevents the conversion of adrenal androgens (e.g., testosterone) to estrogen in peripheral and tumor tissues. As the growth of many breast cancers is stimulated and/or maintained by estrogen, anastrozole helps to treat these cancers by decreasing the levels of circulating estrogens.12,9 Anastrozole has a relatively long duration of action, allowing for once-daily dosing – serum estradiol is reduced by approximately 70% within 24 hours of beginning therapy with 1mg once daily, and levels remain suppressed up to 6 days following cessation of therapy.10
The incidence of ischemic cardiovascular events was increased during anastrozole therapy, and patients with pre-existing ischemic heart disease should consider the risks and benefits of anastrozole before beginning therapy. Anastrozole has also been reported to decrease spine and hip bone mineral density (BMD), so consideration should be given to BMD monitoring in patients receiving long-term therapy.10,8
Mechanism of action
Anastrazole exerts its anti-estrogenic effects via selective and competitive inhibition of the aromatase enzyme found predominantly in the adrenal glands, liver, and fatty tissues.5 Many breast cancers are hormone receptor-positive, meaning their growth is stimulated and/or maintained by the presence of hormones such as estrogen or progesterone.10 In postmenopausal women, estrogen is primarily derived from the conversion of adrenally-produced androgens into estrogens by the aromatase enzyme. By competitively inhibiting the biosynthesis of estrogen at these enzymes, anastrozole effectively suppresses circulating estrogen levels and, subsequently, the growth of hormone receptor-positive tumors.5,9
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Arimidex pills, also known as Anastrozole, are some of the best products for thwarting estrogenic issues that arise due to anabolic steroids.
While at it, A-Tech Labs Anastrazole pills are the most premium grade Arimidex pills you can find online; making them part of your cycle will help counteract short–term and long–term effects that come with using AAS. The round white pills have an identification logo on the surface and are widely considered to ensure a safe cycle.
Properties of Arimidex Anti Estrogen/Testosterone
Arimidex pills’ effectiveness is pegged on their ability to play two integral roles simultaneously; one, they help lower estrogen levels, and two, they actively boost testosterone levels.
These two properties render Arimidex pills valuable for use as protection during both intra and post-cycle. However, their potential as a protective agent is not comparable to that of Nolvadex, so most users tend not to rely entirely on it.
Estrogen protection agents have two main categories: Selective Estrogen Receptor Modulators (SERM’s) and Aromatase Inhibitors (AI’s).
SERM’s estrogen protection agents play the role of controlling the levels of “female hormone.” Although they don’t suppress estrogen levels completely, they help to quash them to a level where they are doubtful to cause adverse effects.
Edema (water retention) is the most notable side effect to expect as it may lead to an unprecedented rise in blood pressure.
A portion of AAS users also has to deal with gynecomastia’s dreaded trouble (male breast tissue development) as another major adverse effect. However, it’s improbable to occur unless, of course, you mess up with dosages or perhaps use potent products.
If the cycle performed is too strong, then SERM’s cannot guarantee safety on their own. That means you will possibly have to deal with gynecomastia symptoms which is why you need a more potent product to subdue them, including AI.
Arimidex tabs are known to elevate the release of both luteinizing and follicle-stimulating hormones, which are considered crucial for testosterone synthesis.
This can play a crucial role in cushioning the “male hormone” to ensure it doesn’t plummet too low when using anabolic steroids.
Boosting testosterone is also key as it plays an important role in lowering the production of estrogen. This, in fact, is why Arimidex tablets are also considered good for use during the post cycle phase as they aid in balancing hormones so that testosterone can thrive.
Arimidex is a treatment for breast cancer that some bodybuilders take to reduce anabolic steroids’ side effects. The drug lowers estrogen levels in the body. Bodybuilders who take anabolic steroids to increase muscle mass and improve athletic performance can experience various symptoms.
Benefits and Side Effects of Arimidex
Arimidex pills are primarily used as a safety mechanism for canceling out the side effects of AAS.
The following are some of the pros of using Arimidex pills in your anastrozole cycle:
- Shield against subcutaneous water retention
- Safeguard against the effects of gynecomastia
- Enhance testosterone levels
Combined, these merits are proof enough that Arimidex helps guard you against any potential problems that may occur in your cycle.
Although these tabs contain a pharmaceutical-grade compound, it doesn’t mean that they don’t have potential side effects too.
And while the issues may not be that grave, users have reported the following side effects after using Arimidex.
- Stomach discomfort
- Headaches and blurred vision
- High blood pressure
- Joint pains
All in all, anastrozole’s side effects are a rare occurrence, provided you follow the right guidelines and dosages when administering the pills.
Arimidex vs Tamoxifen
Earlier ATAC results found that Arimidex was more effective than tamoxifen in reducing the risk of recurrence of early-stage, hormone-receptor-positive breast cancer in postmenopausal women. Other studies comparing tamoxifen to the other two aromatase inhibitors (Aromasin and Femara) have shown similar results.
Arimidex Dosage and Cycles
For the intro or post cycle cure plan, take between 0.5-1 OED of Arimidex per day for the best results.
Concerning the duration of administration, be sure to maintain the system’s right levels, provided you’re still in the cycle; this helps shield you from various estrogenic complications.
Since it takes 7 days for this product to stabilize in the bloodstream, consider taking it for 7 days before beginning your cycle when it’s meant for intra-cycle purposes.
For some users, anastrozole pills are best suited for bodybuilding purposes instead of protection during intra-cycles. In the last 10-14 days of a cutting cycle, they help to enhance muscular dryness.
In that case, you would need to administer 1mg every day– an outstanding trick for eliminating any subcutaneous water that might form.
When using it for PCT purposes, go with the appropriate intra cycle guidelines, whereby it should last for 4 weeks to aid in the reinstatement of testosterone.
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Before being released into the market, each bit of A-Tech Labs Anastrazole is:
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Talk with your doctor for medical advice while taking this medication