What is Testo Pills, Testosterone undecanoate used for?
Men use testosterone undecanoate with low or no testosterone due to certain medical conditions (hypogonadism). Testosterone belongs to a class of drugs known as androgens. It helps the body develop and maintain male sexual characteristics (masculinity), such as a deep voice and body hair.
- Product and Laboratory: Testosterone Undecanoate by A-Tech Labs
- Effects: increased motivation, increased power performance, increased libido, increased endurance
- Ingredients: Testosterone Undecanoate
- Form: Oral
- Concentration: 50 mg/tabs
- Presentation: 50 tabs
- Dosage: 250-1000 mg/week
Male Beginners Intermediate Advanced Female 120-250 per day 250-500 per day 500-100mg per day N/A
- Stack: Nolvadex, Nandrolone Decanoate
- Level: Suitable for all users
It is worth noting that Testosterone Undecanoate by A-Tech Labs is one of the safest anabolic steroids. In rare cases appears manifestations of side effects like rashes, loss of appetite, headache. But, using at recommended dosage, adverse effects are not observed.
Testosterone Tablets are used for boosting testosterone levels and very popular among bodybuilders if you want to build and muscles.
Testosterone undecanoate is indicated for replacement therapy in adult males with conditions linked to an absence or deficiency in endogenous testosterone production. 14
Testosterone plays a key role in male sexual differentiation and regulates hematopoiesis, body composition, and bone metabolism. As a result, testosterone replacement therapy in males with hypogonadism can improve sexual function, increased lean body mass, bone density, erythropoiesis, prostate size, and changes in lipid profiles. 6
Mechanism of action
Testosterone is produced by Leydig cells and exerts its effects by binding to androgen receptors throughout the body. 5 Testosterone affects the voice, genitalia, mood and influences muscle growth and protein expression. 5 Accordingly, males with low testosterone levels often experience decreased libido, fatigue, mood changes, and dysphoria. 5 Exogenous sources of testosterone are designed to mimic the effects of endogenous testosterone.
The absorption of testosterone undecanoate varies based on the formulation. The intramuscular formulation of testosterone esters is suspended in oil and is absorbed from the lipid phase. Testosterone is released when tissue esterases cleave the undecanoic acid side chain. 14
The oral formulation of testosterone undecanoate is also formulated as a prodrug, is best absorbed with food, and ideal absorption occurs when taken with a meal containing at least 30 g of fat. Label
Volume of distribution
Circulating testosterone is highly protein-bound, with about 40% bound to sex hormone-binding globulin (SHBG). A large percentage of the remaining hormone is loosely bound to albumin and other plasma proteins. Only about 2% of testosterone is unbound. Label
The side chain of testosterone undecanoate is cleaved by nonspecific esterases when it enters circulation, and the beta-oxidation pathway metabolizes the undecanoic acid side chain. 9Label The resulting Testosterone molecule is then metabolized to dihydrotestosterone (DHT) by the enzyme 5-alpha reductase. 15 DHT is reduced by 3-alpha-hydroxysteroid dehydrogenase (major) and 3-beta-hydroxysteroid dehydrogenase before being glucuronidated and cleared by the kidneys. 15 It should be noted that testosterone is metabolized to several other 17-keto steroids in the body. Label
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Route of elimination
The majority (~90%) of an intramuscularly administered dose of testosterone is conjugated and eliminated in the urine. Approximately 6% of the dose is eliminated, primarily unconjugated in the feces. Label
Based on one source, Testosterone undecanoate in castor oil (for intramuscular injection) has a half-life of 33.9 days, allowing it to maintain serum levels in the normal range for over 6 weeks. 7 It should be noted that the half-life of testosterone reported in the literature is inconsistent. 14
There is evidence that in adolescent users, testosterone at supra-therapeutic levels may contribute to aggressive behavior and increased rates of suicide. 8 However, testosterone does not appear to affect cognition in adult men receiving testosterone replacement therapy negatively and may, in fact, benefit cognitive function.8 Administration of exogenous testosterone affects normal physiological hormonal regulation and ultimately depresses the release of follicle-stimulating hormone and luteinizing hormone, resulting in reduced sperm production.8 This should be considered before initiating testosterone in males who wish to start or grow a family.8 Increased levels of testosterone can also cause increased sebum production. Therefore acne may be observed in patients taking exogenous testosterone.8 Since testosterone is converted to estrogen in the body by aromatization, males taking testosterone replacement may experience gynecomastia and/or breast pain. 8