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Tramadol has mu-opioid agonist activity. Tramadol HCl 37.5
mg/Acetaminophen 325 mg tablets, a tramadol-containing product, maybe
sought by drug abusers and people with addiction disorders and may even
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likelihood of misuse, abuse, or diversion. Misuse or abuse poses a
real risk to the abuser which could cause overdose and death (see
DRUG ABUSE AND DEPENDENCE and OVERDOSAGE).
The analgesic action of tramadol just isn’t fully understood,
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norepinephrine along with its relatively-weak -opioid receptor agonism.
The contribution of non-opioid activity is demonstrated through the fact
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opioid receptor antagonist naloxone.
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