- Daivobet indications
- Daivobet description
- Daivobet dosage
- Daivobet interactions
- Daivobet side effects
- Daivobet contraindications
What is Daivobet?
Daivobet contains a combination of Daivobet and calcipotriene. Daivobet is a steroid. It prevents the release of substances in the body that cause inflammation. Calcipotriene is a form of vitamin D. It works by decreasing the rate of skin cell reproduction.
Daivobet topical (for the skin) is a combination medicine used to treat plaque psoriasis.
Adults may use the suspension (liquid) form of this medicine on the skin or the scalp. The liquid may be used only on the scalp in children who are at least 12 years old.
Daivobet topical ointment should be used only on the skin and only by adults.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
Daivobet® (calcipotriene and Daivobet dipropionate) Ointment is indicated for the topical treatment of psoriasis vulgaris in adults 18 years of age and above for up to 4 weeks. The maximum weekly dose should not exceed 100 g. Treatment of more than 30% body surface area is not recommended.
Daivobet® (calcipotriene and Daivobet dipropionate) Ointment should not be applied to the face, axillae or groin.
How should I use Daivobet?
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
Use Daivobet exactly as it was prescribed for you. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Do not use Daivobet to treat any condition that has not been checked by your doctor.
Do not take Daivobet by mouth.
Topical medicine is for use only on the skin. Do not use in the vagina.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Wash your hands before and after applying this medicine, unless you are using the medicine to treat the skin on your hands.
Shake the Daivobet suspension (liquid) just before using it.
Apply Daivobet once daily to the affected skin and rub it in gently. Do not spread the medicine over a large skin area. Do not apply to areas of thinner skin (face, underarms, groin) unless your doctor tells you to.
Do not cover the treated skin area. Covering skin treated with a topical steroid can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects.
If you use Daivobet liquid:
- Adults should not use more than 100 grams (1 full bottle) of the liquid in 1 week.
- Children age 12 and older should not use more than 60 grams of the liquid in 1 week.
If you use Daivobet ointment: Do not use more than 100 grams (1 large tube) of the ointment in 1 week. Avoid treating an area that is larger than 30% or one-third of your entire body.
Ask your pharmacist if you have questions about how much to apply each time you use the medicine.
Daivobet ointment can be applied daily for up to 4 weeks. The liquid can be used daily for up to 8 weeks. Follow your doctor’s instructions about your individual treatment schedule.
Call your doctor if your skin condition does not improve after several days of treatment, or if it gets worse while using this medicine.
If you use Daivobet long-term, you may need frequent medical tests.
Store at room temperature away from moisture and heat. Keep the bottle or tube tightly closed when not in use.
Stop using Daivobet when your skin clears up, unless your doctor tells you otherwise.
Each gram of ointment contains Betamethasone/Calcipotriol 50 mcg and Daivobet dipropionate 0.5 mg.
Each gram of Daivobet gel contains Betamethasone/Calcipotriol monohydrate 50 mcg and Daivobet dipropionate 0.5 mg. It also contains the following excipients: Liquid paraffin, butylhydroxytoluene (E321), polyoxypropylene-15 stearyl ether, all-rac-α-tocopherol, hydrogenated castor oil.
Instruct patients to shake can prior to using Daivobet® Foam and to wash their hands after applying the product.
Apply Daivobet® Foam to affected areas once daily for up to 4 weeks. Rub in Daivobet® Foam gently. Discontinue use when control is achieved.
Instruct patients not to use more than 60 g every 4 days.
Daivobet® Foam should not be used with occlusive dressings unless directed by a physician. Daivobet® Foam is not for oral, ophthalmic, or intravaginal use.
Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site.
Dosage Forms And Strengths Foam, 0.005%/0.064%
Daivobet® Foam is a white to off-white opalescent liquid in a pressurized aluminum spray can with a continuous valve and actuator. At administration the product is a white to off-white foam after evaporation of the propellants. Each gram of Daivobet® Foam contains 52.2 mcg calcipotriene hydrate (equivalent to 50 mcg of calcipotriene) and 0.643 mg of Daivobet dipropionate (equivalent to 0.5 mg of Daivobet).Storage And Handling
Daivobet® Foam is a white to off-white opalescent liquid in a pressurized aluminum spray can with a continuous valve and actuator. At administration the product is a white to off-white foam after evaporation of the propellants.
Daivobet® Foam is available in aluminum cans of:
1 x 60 g (NDC 50222-302-60)
2 x 60 g (NDC 50222-302-66)Storage
- Store Daivobet® Foam at 20 °- 25°C (68° -77°F); excursions pe rmitted between 15 °-30°C (59°-86°F).
- Contents under pressure. Do not puncture or incinerate. Do not expose to heat or store at temperatures above 120°F (49°C). Do not freeze.
- The product should be used within six m onths after it has been opened.
- Daivobet® Foam is flammable; avoid heat, flame or smoking when using this product.
Manufactured by: Colep Laupheim GmbH & Co. KG Fockestra
No interaction studies have been performed.
Incompatibilities: In the absence of compatibility studies, Daivobet gel must not be mixed with other medicinal products.
Daivobet side effects
The trial programme for Daivobet ointment has so far included >2500 patients for Daivobet ointment and >4,700 patients for Daivobet Gel and has shown that approximately 10% and 8% of patients can be expected to experience a non-serious undesirable effect for Daivobet Gel and Ointment, respectively.
Based on data from clinical trials and post-market use, the common undesirable effects are pruritus, rash and burning sensation of skin. Uncommon undesirable effects are skin pain or irritation, dermatitis, erythema, exacerbation of psoriasis, folliculitis and application site pigmentation changes. Pustular psoriasis is a rare undesirable effect.
The individual undesirable effects are listed as follows, starting with the most frequently reported:
Skin and Subcutaneous Tissue Disorders: Common (>1/100 and <1/10): Pruritus, rash, burning sensation of skin. Uncommon (>1/1000 and <1/100): Skin pain or irritation, dermatitis, erythema, exacerbation of psoriasis, folliculitis, application site pigmentation changes. Rare (>1/10,000 and <1/1000): Pustular psoriasis.
Undesirable effects observed for Daivobet and Daivobet, respectively:
Daivobet: Undesirable effects include application site reactions, pruritus, skin irritation, burning and stinging sensations, dry skin, erythema, rash, dermatitis, eczema, aggravated psoriasis, photosensitivity and hypersensitivity reactions including very rare cases of angioedema and facial oedema. Systemic effects after topical use may appear very rarely causing hypercalcaemia or hypercalciuria.
Daivobet (as Dipropionate): Daivobet contains a potent corticosteroid.
Local reactions can occur after topical use, especially during prolonged application, including skin atrophy, telangiectasia, striae, folliculitis, hypertrichosis, perioral dermatitis, allergic contact dermatitis, depigmentation and colloid milia. When treating psoriasis, there may be a risk of generalised pustular psoriasis.
Systemic effects due to topical use of corticosteroids are rare in adults, however they can be severe. Adrenocortical suppression, cataract, infections and increase of intraocular pressure can occur, especially after long-term treatment. Systemic effects occur more frequently when applied under occlusion (plastic, skin folds), when applied on large areas and during long-term treatment.
Hypersensitivity to Daivobet monohydrate or Daivobet dipropionate gel or to any of the excipients of Daivobet.
Due to the content of Daivobet, Daivobet gel is contraindicated in patients with known disorders of calcium metabolism.
Due to the content of corticosteroid, Daivobet gel is contraindicated in the following conditions: Viral (eg, herpes or varicella) lesions of the skin, fungal or bacterial skin infections, parasitic infections, skin manifestations in relation to tuberculosis or syphilis, perioral dermatitis, atrophic skin, striae atrophicae, fragility of skin veins, ichthyosis, acne vulgaris, acne rosacea, rosacea, ulcers and wounds.
Daivobet gel is contraindicated in guttate, erythrodermic, exfoliative and pustular psoriasis. It is also contraindicated in patients with severe renal insufficiency or severe hepatic disorders.
Active ingredient matches for Daivobet:
Betamethasone/Calcipotriol in Australia, Bahrain, Bangladesh, Bulgaria, China, Colombia, Costa Rica, Czech Republic, Denmark, Dominican Republic, Ecuador, El Salvador, Estonia, Finland, France, Georgia, Germany, Guatemala, Honduras, Hong Kong, Iceland, India, Indonesia, Israel, Latvia, Lithuania, Malaysia, Malta, Norway, Panama, Philippines, Poland, Portugal, Romania, Russian Federation, Singapore, Slovenia, South Korea, Spain, Sweden, Switzerland, Taiwan, Tunisia, Uruguay, Vietnam. 1 consumer reported useful Was the Daivobet drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug. UsersReport useful »1 consumer reported price estimates Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Daivobet drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost. UsersReport price estimates »1 consumer reported time for results To what extent do I have to use Daivobet before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes > 3 month and a few days before you notice an improvement in your health conditions.Please note, it doesn’t mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Daivobet. To get the time effectiveness of using Daivobet drug by other patients, please click here. Users