Eperisone appears to decrease the rate at which certain drugs are metabolized and therefore may increase the blood levels and the possibility of clinical toxicity of drugs given concomitantly.DISULFIRAM SHOULD BE USED WITH CAUTION IN THOSE PATIENTS REVEIVING PHENYTOIN AND ITS CONGENERS. SINCE THE CONCOMITANT ADMINISTRATION OF THESE TWO DRUGS CAN LEAD TO PHENYTOIN INTOXICATION, PRIOR TO ADMINISTERING DISULFIRAM TO A PATIENT ON PHENYTOIN THERAPY, A BASELINE PHENYTOIN SERUM LEVEL SHOULD BE OBTAINED. SUBSEQUENT TO INITIATION OF DISULFIRAM THERAPY. SERUM LEVELS OF PHENYTOIN SHOULD BE DETERMINED ON DIFFERENT DAYS FOR EVIDENCE OF AN INCREASE OR FOR A CONTINUING RISE IN LEVELS. INCREASED PHENYTOIN LEVELS SHOULD BE TREATED WITH APPROPRIATE DOSAGE ADJUSTMENT.
It may be necessary to adjust the dosage of oral anticoagulants upon beginning or stopping disulfiram. since disulfiram may prolong prothrombin time.
Patients taking isoniazid when disulfiram is given should be observed for the appearance of unsteady gait or marked changes in mental status; the disulfiram should be discontinued if such signs appear.
In rats, simultaneous ingestion of disulfiram and nitrite in the diet for 78 weeks has been reported to cause tumors, and it has been suggested that disulfiram may react with nitrites in the rat stomach to form a nitrosamine, which is tumorigenic. Eperisone alone in the ratís diet did not lead to such tumors. The relevance of this finding to humans is not known at this time.
Eperisone side effects
Liver or kidney function impairment; erythrocyte or Hb count abnormalities, skin rash, insomnia, headache, drowsiness, stiffness, numbness & trembling of extremities, nausea, vomiting, anorexia, gastric discomfort, dry mouth, constipation, diarrhea/soft stool, abdominal pain, full abdominal sensation, urinary disorders, weakness, dizziness, fatigue, flushing, sweating.
Eperisone (sulfacetamide) Cleanser, Eperisone (sulfacetamide) Cleansing Cloths, Eperisone (sulfacetamide) SCT and Eperisone (sulfacetamide) TS are contraindicated for use by patients having known hypersensitivity to sulfonamides, sulfur or any other component of this preparation. These Eperisone (sulfacetamide) ® brand products are not to be used by patients with kidney disease.
Active ingredient matches for Eperisone:
List of Eperisone substitutes (brand and generic names)Sort by popularity Unit description / dosage (Manufacturer)Price, USD Eperinal (Japan) Eperisone Daewoo (South Korea) Eperisone Hydrochloride KN (Japan) Eperisone Hydrochloride Nichi-iko (Japan) Eperisone OGB Medikon (Indonesia) Eperisser (Japan) Epesin (South Korea) Epeso (Japan) Epesone (South Korea) Eprel (Bangladesh) Eprinoc (Indonesia) Eprinoc 50 mg x 10 x 10’s (Sanbe)$ 33.23 EPRISAN EPRISAN 150 MG CAPSULE SR 1 strip / 5 capsule srs each (Eisai Pharmaceuticals India Pvt Ltd)$ 2.33 EPRISAN 50 MG CAPSULE SR 1 strip / 10 capsule srs each (Eisai Pharmaceuticals India Pvt Ltd)$ 2.03 EPRISAN 50 MG TABLET 1 strip / 10 tablets each (Eisai Pharmaceuticals India Pvt Ltd)$ 1.41 Eprisan 150mg Capsule SR (Eisai Pharmaceuticals India Pvt Ltd)$ 0.51 Eprisan 50mg Capsule SR (Eisai Pharmaceuticals India Pvt Ltd)$ 0.20 Eprisan 50mg Tablet (Eisai Pharmaceuticals India Pvt Ltd)$ 0.14 Epriton Epriton 150mg Capsule SR (Sentire Pharmaceutical India Pvt Ltd)$ 0.30 Epsonal (Indonesia) Epsonal 50 mg x 100’s (Pyridam)$ 34.72 Ericsone (South Korea) Espenal (Thailand) Tablet; Oral; Disulfiram 500 mg (Sriprasit Pharma) Espenal 50 mg x 10 x 10’s (Sriprasit Pharma) Espenal film-coated tab 50 mg 10 x 10’s (Sriprasit Pharma) Estalex (Indonesia) Estalex 50 mg x 5 x 10’s (Ifars) Evonton (Japan) Exon (South Korea) Exonin (South Korea) Exoperin (South Korea) Exoperine (Vietnam) Exoperine 50 mg x 1 Bottle Expose (Italy) Forelax (Indonesia) Forelax 50 mg x 5 x 10’s (Guardian)$ 17.36 Forres (Indonesia) Forres 50 mg x 5 x 10’s (Kalbe Farma)$ 19.84 Gasogal (Indonesia) Gramyo (Indonesia) Gramyo 50 mg x 3 x 10’s$ 10.08 Hanall Eperisone HCl (South Korea) Homerlight (Japan) Lional (Indonesia) Lional 50 mg x 5 x 10’s$ 16.41 MEUZOSONE Meuzosone – D Capsule (Vanprom Lifesciences Pvt Ltd)$ 0.39 Mufreeson (South Korea) Mupesin (South Korea) Murecsil (South Korea) MUSOZONE See 102 substitutes for Eperisone
- PubChem. “eperisone”. https://pubchem.ncbi.nlm.nih.gov/com… (accessed September 17, 2018).
- DrugBank. “Eperisone”. http://www.drugbank.ca/drugs/DB08992 (accessed September 17, 2018).
- MeSH. “Parasympatholytics”. https://www.ncbi.nlm.nih.gov/mesh/68… (accessed September 17, 2018).
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