Injectable B12, 1000mcg
Active Ingredients: Cyanocobalamin 1000 mcg.
Injectable Vitamin B12 in 10ml vials. Cyanocobalamin concentration 1000 mcg per ml packaged in convenient multi-use vials.
Vitamin B₁₂, also known as cobalamin, is a water-soluble vitamin involved in the metabolism of every cell of the human body. It is one of eight B vitamins. It is a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism.
$29.00 – $84.00
Vitamin B 12 Injection
Quality: B12 Direct works only with the country of origin government-licensed suppliers. We have independently tested our injectable vitamin B12 for quality and safety at Mérieux NutriSciences (Vancouver Canada). Packaging may differ from our website depending on the supplier, but we certify that the contents of our B12 are standard and true to description.
What is Ampavit
Ampavit is a man-made form of Ampavit. Ampavit is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.
Ampavit nasal is used to treat Ampavit deficiency in people with pernicious anemia and other conditions.
Ampavit nasal is usually given after treatment with an injection form of this medicine.
Ampavit nasal may also be used for purposes not listed in the Ampavit guide.
Ampavit side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have signs of low potassium–confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.
Common side effects may include:
- runny nose, sneezing;
- stuffy nose, sinus pain, sore throat, cough with mucus;
- headache, dizziness;
- joint pain; or
- itching or rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects
Usual Adult Dose for Pernicious Anemia: Parenteral:
Initial dose: 100 mcg intramuscularly once a day for 7 days. If there is clinical improvement and a reticulocyte response, 100 mcg intramuscularly once every other day for 7 days, then once every 3 to 4 days for another 2 to 3 weeks is recommended. Most patients require monthly injections of 100 to 1000 mcg intramuscularly for life.
Nasal Spray or Gel:
Alternatively, Ampavit nasal spray or nasal gel 500 mcg intranasally to one nostril once a week may be administered to patients with pernicious anemia who require maintenance of normal hematologic status following intramuscular Ampavit and who have no nervous system involvement. However, if the patient is not adequately maintained with Ampavit nasal, intramuscular Ampavit administration must be resumed.
Usual Adult Dose for B12 Nutritional Deficiency: Oral: 25 to 250 mcg once a day.
Nasal Spray or Gel:
(Nascobal) 500 mcg intranasally in one nostril once a week
(CaloMist) 25 mcg in each nostril once a day (total dose of 50 mcg). May be increased to 50 mcg in each nostril once a day.
Usual Adult Dose for Schilling Test: 1 mcg radiolabeled Ampavit orally once after urinary voiding. A 24-hour urinary collection is immediately begun. At 2 hours an injection of Ampavit 1,000 mcg intramuscularly is given to “flush” the patient of the absorbed radiolabeled drug. The percentage of radiolabeled B12 excreted in the urine is a measure of how much-labeled drug was absorbed. Normally 7% or more of a dose is excreted in 24 hours.
Usual Pediatric Dose for Pernicious Anemia: Neonates and Infants: Intramuscular or Subcutaneous: 0.2 mcg/kg for 2 days, followed by 1000 mcg/day for 2 to 7 days; maintenance: 100 mcg/month.
Children: Intramuscular or Subcutaneous: 30 to 50 mcg/day for 2 or more weeks (to a total dose of 1000 mcg), then follow with 100 mcg/month.
Usual Pediatric Dose for B12 Nutritional Deficiency: Intramuscular or Subcutaneous: Initial: 0.2 mcg/kg for 2 days followed by 1000 mcg/day for 2 to 7 days followed by 100 mcg/week for a month or 100 mcg/day for 10 to 15 days, then once or twice weekly for several months. May taper to 60 mcg every month. For malabsorptive causes of B12 deficiency, monthly maintenance doses of 100 mcg have been recommended.
Active ingredients: Cyanocobalamin
Select the most affordable brand or generic drug
StrengthQuantityPrice, USDCountry AnivitB12 B 12 Ankermann B Twelve P B12 Ankermann Cobamin Ophth Soln Cobolin-M Creliverol-12 Cromaton Cromatonbic B12 Cyancobalamin Biopharm Cyanocobalamin Biostimulator Cynomin-H Cyomin Cyomin 50 mg Capsule $0.23 Cyomin 100 mg Capsule $0.39 Ecovitamine B12 Eligen B12 Emicobal Haemo-Vibolex Jaba B12 Lophakomp-B 12 Nascobal spray Neurobene Osteo Biflex Advanced Triple Strength mg80 $32.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA mg80 $32.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK Reticulogen Sicovit Softear 0.02% Vit-B12-Denk Vitamin B 12 3 MG/ML Injectable Solution Vitamin B 12 Lichtenstein Vitamin B 12 Wiedemann Vitamin B12 1200mcg Timed Release (jamieson) 1200 mcg60 $9.99Canada, Mauritius, Singapore, Turkey, UK, USA 1200 mcg60 $9.99Canada, Mauritius, Singapore, Turkey, UK, USA Vitamin B12 A.N.H. Vitamin B12 Ceva Vitamin B12 Chi Sheng Vitamin B12 Cyanocobalamin Injection Vitamin B12 Freeda Vitamin B12 IPI Vitamin B12 IPI 50 mcg x 50’s $0.17 Vitamin B12 Injection 1000 mcg/ml1 $24.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA 1000 mcg/ml3 $75.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA 1000 mcgml(10x1mlampoules)1 box$21.99Canada, Mauritius, Singapore, Turkey, UK, USA 1000 mcgml(30mlvial)1 vial$34.99Canada, Mauritius, Singapore, Turkey, UK, USA Vitamin B12 Kimia Farma Vitamin B12 Kimia Farma 50 mcg x 1000’s $2.37 Vitamin B12 Kimia Farma 500 mcg/5 mL x 100’s $0.74 Vitamin B12 Kobayashi Vitamin B12 Leciva Vitamin B12-Injektopas Vitamina B12 Vitamine B12 Vitamine B12 Chauvin Vitamine B12 Horus Pharma Vitamine B12 Nichi-iko Vitamine B12 Sterop Vitamine B12 Vétoquinol Vitarubin superconc. Yu Hai Xiang cyanocobalamin 3 MG/ML Injectable Solution vitamin B12-loges
Ampavit – Frequently asked Questions
Can Ampavit be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It’s wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Who should not take Ampavit?
You should not use this medicine if you are allergic to Ampavit or cobalt, or if you have Leber’s disease. Ampavit can lead to optic nerve damage (and possibly blindness) in people with Leber’s disease.
To make sure Ampavit nasal is safe for you, tell your doctor if you have:
- cold or allergy symptoms that affect your nose (sinus congestion, sneezing);
- kidney or liver disease;
- iron or folic acid deficiency;
- any type of infection; or
- if you are receiving any medication or treatment that affects bone marrow.
FDA pregnancy category C. It is not known whether Ampavit nasal will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
Ampavit nasal can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Do not give this medication to anyone under 18 years old without medical advice.
How should I take Ampavit?
Ampavit nasal is usually given once per week. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
This medicine comes with patient instructions for safe and effective use and directions for priming the nasal spray. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
To use the nasal spray:
- Blow your nose gently. Keep your head upright and insert the tip of the bottle into one nostril. Press your other nostril closed with your finger. Spray the medicine into your nose and gently sniff at the same time. Then use the spray in your other nostril.
- Do not blow your nose for at least a few minutes after using the nasal spray.
- Wait several hours after using Ampavit nasal spray before using any other nasal medicines your doctor has prescribed.
- Clean the tip of the spray with a clean tissue and recap.
Tell your doctor if you have a prolonged illness that causes sinus congestion. Ampavit nasal may not work as well if you have a stuffy nose.
Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.
While using Ampavit nasal, you may need blood tests every 3 to 6 months. Based on the results of these tests, your doctor may occasionally change your dose or recommend a Ampavit injection.
Use Ampavit nasal regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
To treat pernicious anemia, you may have to use Ampavit for the rest of your life. Do not stop using the medicine unless your doctor tells you to. Untreated Ampavit deficiency can lead to a recurrence of anemia and irreversible nerve damage.
Pernicious anemia is also treated with folic acid to help maintain red blood cells. However, folic acid will not treat Ampavit deficiency and will not prevent possible damage to the spinal cord. Use all of your medications as directed.
Store in an upright position at room temperature, away from moisture, heat, and light. Do not freeze.
What other drugs will affect Ampavit?
Other drugs may interact with Ampavit nasal, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Can Ampavit be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such a case requires special attention.
Can Ampavit be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
General Injectable B12 Cyanocobalamin Information
Visit our Vitamin B12 Injectable Information page. For information on the clinical pharmacology of injectable vitamin B12 cyanocobalamin including contraindications and precautions visit the US National Library of Medicine – DailyMed Cyanocobalamin.